Mk677 10mg

$65.00

🔬 Key Studies on MK‑677 (Ibutamoren)

1. Hip Fracture Recovery Phase IIb Study

Title: MK-0677 (ibutamoren mesylate) for treatment of patients recovering from hip fracture

A multicenter, randomized, placebo-controlled Phase IIb clinical trial investigating MK‑677 in elderly patients after hip fracture.
Outcomes included mobility, bone healing, and functional recovery. Reddit+15PubMed+15Reddit+15

2. Healthy Elderly Subjects – GH and IGF‑1

Title: Effects of MK‑677 on somatic growth, GH/IGF‑1 axis and body composition in elderly subjects

Daily 10–25 mg dosing in adults 64–81 years old showed up to 97% increase in GH and 88% in IGF‑1.
Increased lean body mass by approximately 3 kg with no change in fat mass. Raised insulin and prolactin levels modestly. PubMed+5PMC+5Wikipedia+5Wikipedia

3. Obese Young Males – Bone Markers

Title: Short‑term MK‑677 treatment increases markers of bone turnover in obese males

In healthy men with BMI > 30, 25 mg/day for 8 weeks induced significant increases in bone formation and resorption markers (e.g., osteocalcin, IGFBP‑5). PubMed+1chemdatabank.com+1

4. Alzheimer Disease Progression Study

Title: MK‑677 in mild to moderate Alzheimer’s disease: 12‑month randomized trial

563 patients received 25 mg/day or placebo for a year. IGF‑1 increased significantly, but no improvement in cognitive or functional outcomes was observed. Reddit+15PubMed+15PMC+15

5. Preclinical Animal Study – Rat Model

Title: Effect of MK‑677 on somatic growth in rats

Animal model confirming GH secretagogue activity and studying metabolic effects and safety endpoints in lab rodents. chemdatabank.com+2PubMed+2PubMed+2

Category: Sarms

Description
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MK-677 (Ibutamoren) – 10mg Dry Fill Powder Capsules

Provided by Combat Research – Research-Grade Peptides

CAS Number: 159634-47-6
Other Names: MK-0677, L-163,191, Oratrope
IUPAC Name:
2-amino-2-methyl-N-[(2R)-1-(1-methylsulfonylspiro[2H-indole-3,4′-piperidine]-1′-yl)-1-oxo-3-(phenylmethoxy)propan-2-yl]propanamide mesylate
Molecular Formula: C₂₇H₃₆N₄O₅S·CH₃SO₃H
Molecular Weight: 624.77 g/mol

Product Overview

MK-677 (Ibutamoren) is a non-peptide, orally active growth hormone secretagogue under ongoing investigation for its ability to increase growth hormone (GH) and IGF-1 levels. At Combat Research, we offer 20mg dry fill powder capsules for research use only, specifically designed for consistency, purity, and ease of dosing in controlled laboratory environments.

This formulation is ideal for studies related to:

Muscle preservation during energy deficit
Endocrine system regulation under operational stress
Age-related hormonal decline and metabolism research
Performance resilience in tactical or combat models

Product Specifications

Form: Dry Fill Powder Capsules
Concentration: 20 mg per capsule
Appearance: Off-white to light tan powder in clear or opaque gelatin capsule
Purity: ≥98% (HPLC Tested)
Grade: Research Use Only (RUO)

Each unit is securely packaged with tamper-evident seals and produced under strict lab handling standards to maintain stability and prevent cross-contamination.

Research Use Compliance

This product is intended solely for research purposes, including but not limited to:

University-based hormone studies
Military and tactical performance R&D
Public and private laboratory research involving endocrine responses

Cited in studies found on PubMed, NIH.gov, and ClinicalTrials.gov.

Important Regulatory Note

NOT approved by the FDA for human or veterinary use
Supplied for Research Use Only per 21 CFR 312.2(b)
No therapeutic or diagnostic claims are made or implied
Sale is restricted to qualified labs, institutions, or licensed professionals

Disclaimer

Disclaimer: MK-677 (Ibutamoren) capsules sold by Combat Research are for laboratory research only and are not for human consumption. This product is not a drug, food, or dietary supplement and should not be used in any clinical or therapeutic application. All buyers must be qualified professionals or institutions. Use of this product in any manner not consistent with its labeling may violate federal law.